diff --git a/var/spack/repos/builtin/packages/gromacs/package.py b/var/spack/repos/builtin/packages/gromacs/package.py
index 70b7f5e0234..c680a46955a 100644
--- a/var/spack/repos/builtin/packages/gromacs/package.py
+++ b/var/spack/repos/builtin/packages/gromacs/package.py
@@ -424,6 +424,9 @@ def cmake_args(self):
                 ]
             )
 
+        if self.spec.satisfies("%aocc"):
+            options.append("-DCMAKE_CXX_FLAGS=--stdlib=libc++")
+
         if self.spec.satisfies("@2020:"):
             options.append("-DGMX_INSTALL_LEGACY_API=ON")