diff --git a/var/spack/repos/builtin/packages/hdf/package.py b/var/spack/repos/builtin/packages/hdf/package.py
index 414e21e1e21..9250f68c11c 100644
--- a/var/spack/repos/builtin/packages/hdf/package.py
+++ b/var/spack/repos/builtin/packages/hdf/package.py
@@ -197,6 +197,10 @@ def check(self):
 
     extra_install_tests = join_path("hdf", "util", "testfiles")
 
+    # Filter h4cc compiler wrapper to substitute the Spack compiler
+    # wrappers with the path of the underlying compilers.
+    filter_compiler_wrappers("h4cc", relative_root="bin")
+
     @property
     def cached_tests_work_dir(self):
         """The working directory for cached test sources."""