diff --git a/var/spack/repos/spack_repo/builtin/packages/su2/package.py b/var/spack/repos/spack_repo/builtin/packages/su2/package.py
index 03f43b90527..3321811bb59 100644
--- a/var/spack/repos/spack_repo/builtin/packages/su2/package.py
+++ b/var/spack/repos/spack_repo/builtin/packages/su2/package.py
@@ -159,10 +159,10 @@ def install_mpp(self):
             )
 
     def setup_run_environment(self, env: EnvironmentModifications) -> None:
-        env.set("su2_run", self.prefix.bin)
-        env.set("su2_home", self.prefix)
-        env.prepend_path("path", self.prefix.bin)
-        env.prepend_path("pythonpath", self.prefix.bin)
+        env.set("SU2_RUN", self.prefix.bin)
+        env.set("SU2_HOME", self.prefix)
+        env.prepend_path("PATH", self.prefix.bin)
+        env.prepend_path("PYTHONPATH", self.prefix.bin)
         if "+mpp" in self.spec:
-            env.set("mpp_data_directory", join_path(self.prefix, "mpp-data"))
-            env.prepend_path("ld_library_path", self.prefix.lib)
+            env.set("MPP_DATA_DIRECTORY", join_path(self.prefix, "mpp-data"))
+            env.prepend_path("LD_LIBRARY_PATH", self.prefix.lib)