diff --git a/var/spack/repos/builtin/packages/r-affyio/package.py b/var/spack/repos/builtin/packages/r-affyio/package.py
index 91bd3ddb030..852337f8aca 100644
--- a/var/spack/repos/builtin/packages/r-affyio/package.py
+++ b/var/spack/repos/builtin/packages/r-affyio/package.py
@@ -35,3 +35,4 @@ class RAffyio(RPackage):
 
     version('1.46.0', 'e1f7a89ae16940aa29b998a4dbdc0ef9')
     depends_on('r-zlibbioc', type=('build', 'run'))
+    depends_on('r@3.4.0:3.4.9', when='@1.46.0')