diff --git a/var/spack/repos/builtin/packages/py-h5py/package.py b/var/spack/repos/builtin/packages/py-h5py/package.py
index 39b352e4ae0..384eb4f059b 100644
--- a/var/spack/repos/builtin/packages/py-h5py/package.py
+++ b/var/spack/repos/builtin/packages/py-h5py/package.py
@@ -36,6 +36,7 @@ class PyH5py(PythonPackage):
     depends_on('py-cython@0.29:', type=('build'), when='@3.0.0:')
     depends_on('py-pkgconfig', type='build')
     depends_on('py-setuptools', type='build')
+    depends_on('py-wheel', type='build', when='@3.0.0:')
 
     # Build and runtime dependencies
     depends_on('py-cached-property@1.5:', type=('build', 'run'))