diff --git a/lib/spack/spack/build_systems/cached_cmake.py b/lib/spack/spack/build_systems/cached_cmake.py
index d5121c847b5..5d14693817f 100644
--- a/lib/spack/spack/build_systems/cached_cmake.py
+++ b/lib/spack/spack/build_systems/cached_cmake.py
@@ -298,7 +298,14 @@ def initconfig_hardware_entries(self):
     def std_initconfig_entries(self):
         cmake_prefix_path_env = os.environ["CMAKE_PREFIX_PATH"]
         cmake_prefix_path = cmake_prefix_path_env.replace(os.pathsep, ";")
-
+        complete_rpath_list = ";".join(
+            [
+                self.pkg.spec.prefix.lib,
+                self.pkg.spec.prefix.lib64,
+                *os.environ.get("SPACK_COMPILER_EXTRA_RPATHS", "").split(":"),
+                *os.environ.get("SPACK_COMPILER_IMPLICIT_RPATHS", "").split(":"),
+            ]
+        )
         return [
             "#------------------{0}".format("-" * 60),
             "# !!!! This is a generated file, edit at own risk !!!!",
@@ -307,6 +314,8 @@ def std_initconfig_entries(self):
             "#------------------{0}\n".format("-" * 60),
             cmake_cache_string("CMAKE_PREFIX_PATH", cmake_prefix_path),
             cmake_cache_string("CMAKE_INSTALL_RPATH_USE_LINK_PATH", "ON"),
+            cmake_cache_string("CMAKE_BUILD_RPATH", complete_rpath_list),
+            cmake_cache_string("CMAKE_INSTALL_RPATH", complete_rpath_list),
             self.define_cmake_cache_from_variant("CMAKE_BUILD_TYPE", "build_type"),
         ]