diff --git a/var/spack/repos/builtin/packages/cuda/package.py b/var/spack/repos/builtin/packages/cuda/package.py
index 3e4316b7afe..0879d06edc3 100644
--- a/var/spack/repos/builtin/packages/cuda/package.py
+++ b/var/spack/repos/builtin/packages/cuda/package.py
@@ -35,6 +35,98 @@ class Cuda(Package):
     version('6.5.14', '90b1b8f77313600cc294d9271741f4da', expand=False,
             url="http://developer.download.nvidia.com/compute/cuda/6_5/rel/installers/cuda_6.5.14_linux_64.run")
 
+    # CUDA conflicts taken from official NVidia website
+    #
+    # Note that installation guide for CUDA prior to 8.0 are unavailable,
+    # thus no Spack conflict statements have been implemented prior to
+    # version 8.0.44. These are conflicts from Linux systems analagous
+    # conflicts for Mac can be added later.
+    #
+    # Not all conflicts are expressed, some conflicts are never encountered
+    # in practice. For example, XL compiler on Intel hardware or vice-versa
+    cuda_warning = 'CUDA is not supported by this version of the compiler ' \
+                   'on your architecture.'
+
+    # CUDA 10.0.130
+    # Table 1 from here:
+    # https://docs.nvidia.com/cuda/cuda-installation-guide-linux/index.html
+    cuda_version = '@10.0.130'
+    conflicts('%gcc@8:', when=cuda_version, msg=cuda_warning)
+    conflicts('%llvm@7:', when=cuda_version, msg=cuda_warning)
+    conflicts('%pgi@:17', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@10.0.130 arch=x86_64'
+    conflicts('%intel@:17', when=cuda_version, msg=cuda_warning)
+    conflicts('%intel@19:', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@10.0.130 arch=ppc64le'
+    conflicts('%xl@:12', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@14:15', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@17:', when=cuda_version, msg=cuda_warning)
+
+    # CUDA 9.2.88
+    # https://docs.nvidia.com/cuda/archive/9.2/cuda-installation-guide-linux/index.html
+    cuda_version = '@9.2.88'
+    conflicts('%llvm@6:', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@9.2.88 arch=x86_64'
+    conflicts('%gcc@8:', when=cuda_version, msg=cuda_warning)
+    conflicts('%pgi@:16', when=cuda_version, msg=cuda_warning)
+    conflicts('%intel@18:', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@9.2.88 arch=ppc64le'
+    conflicts('%gcc@6:', when=cuda_version, msg=cuda_warning)
+    conflicts('%pgi@:17', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@:12', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@14:15', when=cuda_version, msg=cuda_warning)
+
+    # CUDA 9.1.85
+    # https://docs.nvidia.com/cuda/archive/9.1/cuda-installation-guide-linux/index.html
+    cuda_version = '@9.1.85'
+    conflicts('%pgi@:16', when=cuda_version, msg=cuda_warning)
+    conflicts('%llvm@5:', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@9.1.85 arch=x86_64'
+    conflicts('%gcc@7:', when=cuda_version, msg=cuda_warning)
+    conflicts('%intel@:16', when=cuda_version, msg=cuda_warning)
+    conflicts('%intel@18:', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@9.1.85 arch=ppc64le'
+    conflicts('%gcc@6:', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@:12', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@14:', when=cuda_version, msg=cuda_warning)
+
+    # CUDA 9.0.176
+    # https://docs.nvidia.com/cuda/archive/9.0/cuda-installation-guide-linux/index.html
+    cuda_version = '@9.0.176'
+    conflicts('%pgi@:16', when=cuda_version, msg=cuda_warning)
+    conflicts('%llvm@4:', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@9.0.176 arch=x86_64'
+    conflicts('%gcc@7:', when=cuda_version, msg=cuda_warning)
+    conflicts('%intel@:16', when=cuda_version, msg=cuda_warning)
+    conflicts('%intel@18:', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@9.0.176 arch=ppc64le'
+    conflicts('%gcc@6:', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@:12', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@14:', when=cuda_version, msg=cuda_warning)
+
+    # CUDA 8.0.x
+    # https://docs.nvidia.com/cuda/archive/8.0/cuda-installation-guide-linux/index.html
+    cuda_version = '@8 arch=x86_64'
+    conflicts('%gcc@7:', when=cuda_version, msg=cuda_warning) 
+    conflicts('%intel@:16', when=cuda_version, msg=cuda_warning)
+    conflicts('%intel@17:', when=cuda_version, msg=cuda_warning)
+    conflicts('%pgi@:16', when=cuda_version, msg=cuda_warning)
+    conflicts('%llvm@4:', when=cuda_version, msg=cuda_warning)
+
+    cuda_version = '@8 arch=ppc64le'
+    conflicts('%pgi', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@:12', when=cuda_version, msg=cuda_warning)
+    conflicts('%xl@14:', when=cuda_version, msg=cuda_warning)
+    conflicts('%llvm', when=cuda_version, msg=cuda_warning)
+
     def setup_environment(self, spack_env, run_env):
         run_env.set('CUDA_HOME', self.prefix)