diff --git a/var/spack/repos/builtin/packages/interproscan/package.py b/var/spack/repos/builtin/packages/interproscan/package.py
index 5639f6caf1b..b9d764f160e 100644
--- a/var/spack/repos/builtin/packages/interproscan/package.py
+++ b/var/spack/repos/builtin/packages/interproscan/package.py
@@ -39,6 +39,7 @@ class Interproscan(Package):
     depends_on('perl-xml-parser', when='@:4.8', type=('build', 'run'))
     depends_on('perl-io-string', when='@:4.8', type=('build', 'run'))
     depends_on('perl-io-stringy', when='@:4.8', type=('build', 'run'))
+    depends_on('perl-db-file', when='@:4.8', type=('build', 'run'))
 
     patch('large-gid.patch', when='@5:')
     patch('non-interactive.patch', when='@:4.8')