diff --git a/var/spack/repos/builtin/packages/musica/package.py b/var/spack/repos/builtin/packages/musica/package.py
new file mode 100644
index 00000000000..94de144f787
--- /dev/null
+++ b/var/spack/repos/builtin/packages/musica/package.py
@@ -0,0 +1,54 @@
+# Copyright Spack Project Developers. See COPYRIGHT file for details.
+#
+# SPDX-License-Identifier: (Apache-2.0 OR MIT)
+
+from spack.package import *
+
+
+class Musica(CMakePackage):
+    """MUSICA - The multi-scale interface for chemistry and aerosols
+
+    MUSICA is a software package which exposes a flexible
+    API for including aerosol and gas-phase chemistry in
+    many contexts across languages and platforms. It is designed to
+    be used in conjunction with other software packages, such as
+    climate models, to provide a comprehensive framework for
+    simulating atmospheric chemistry processes.
+    """
+
+    homepage = "https://github.com/NCAR/musica"
+    url = "https://github.com/NCAR/musica/archive/refs/tags/v0.10.1.tar.gz"
+    git = "https://github.com/NCAR/musica.git"
+
+    maintainers("kshores", "mattldawson", "boulderdaze")
+
+    license("Apache-2.0", checked_by="kshores")
+
+    # Versions
+    version("0.10.1", sha256="edefab03a676a449761997734e6c5b654b2c4f92ce8f1cc66ef63b8ae8ccccf1")
+
+    # Options from CMake
+    variant("mpi", default=False, description="Enable MPI support")
+    variant("openmp", default=False, description="Enable OpenMP support")
+    variant("tests", default=True, description="Enable tests")
+    variant("fortran", default=False, description="Build Fortran interface")
+    variant("micm", default=True, description="Enable MICM support")
+    variant("tuvx", default=True, description="Enable TUV-x support")
+
+    # Dependencies
+    depends_on("cmake@3.21:", type="build")
+    depends_on("cxx", type="build")
+    depends_on("fortran", type="build")
+    depends_on("mpi", when="+mpi")
+
+    def cmake_args(self):
+        args = [
+            self.define_from_variant("MUSICA_ENABLE_MPI", "mpi"),
+            self.define_from_variant("MUSICA_ENABLE_OPENMP", "openmp"),
+            self.define_from_variant("MUSICA_ENABLE_TESTS", "tests"),
+            self.define_from_variant("MUSICA_BUILD_FORTRAN_INTERFACE", "fortran"),
+            self.define_from_variant("MUSICA_ENABLE_MICM", "micm"),
+            self.define_from_variant("MUSICA_ENABLE_TUVX", "tuvx"),
+            self.define("MUSICA_ENABLE_INSTALL", True),
+        ]
+        return args