diff --git a/var/spack/repos/builtin/packages/adios2/package.py b/var/spack/repos/builtin/packages/adios2/package.py
index 5f567373f3d..eb03bcf8de9 100644
--- a/var/spack/repos/builtin/packages/adios2/package.py
+++ b/var/spack/repos/builtin/packages/adios2/package.py
@@ -91,6 +91,9 @@ class Adios2(CMakePackage, CudaPackage):
     conflicts("%intel@:15")
     conflicts("%pgi@:14")
 
+    # ifx does not support submodules in separate files
+    conflicts("%oneapi@:2022.1.0", when="+fortran")
+
     depends_on("cmake@3.12.0:", type="build")
     depends_on("pkgconfig", type="build")