diff --git a/var/spack/repos/builtin/packages/qt/package.py b/var/spack/repos/builtin/packages/qt/package.py
index 87806c431d7..4b76f6fd709 100644
--- a/var/spack/repos/builtin/packages/qt/package.py
+++ b/var/spack/repos/builtin/packages/qt/package.py
@@ -147,6 +147,11 @@ class Qt(Package):
           sha256='84b099109d08adf177adf9d3542b6215ec3e42138041d523860dbfdcb59fdaae',
           working_dir='qtwebsockets',
           when='@5.14: %gcc@11:')
+    # https://github.com/microsoft/vcpkg/issues/21055
+    patch('qt5-macos12.patch',
+          working_dir='qtbase',
+          when='@5.14: %apple-clang@13:')
+
     conflicts('%gcc@10:', when='@5.9:5.12.6 +opengl')
     conflicts('%gcc@11:', when='@5.8')
 
diff --git a/var/spack/repos/builtin/packages/qt/qt5-macos12.patch b/var/spack/repos/builtin/packages/qt/qt5-macos12.patch
new file mode 100644
index 00000000000..242c38c861a
--- /dev/null
+++ b/var/spack/repos/builtin/packages/qt/qt5-macos12.patch
@@ -0,0 +1,12 @@
+diff --git a/src/plugins/platforms/cocoa/qiosurfacegraphicsbuffer.h b/src/plugins/platforms/cocoa/qiosurfacegraphicsbuffer.h
+index e070ba97..07c75b04 100644
+--- a/src/plugins/platforms/cocoa/qiosurfacegraphicsbuffer.h
++++ b/src/plugins/platforms/cocoa/qiosurfacegraphicsbuffer.h
+@@ -40,6 +40,7 @@
+ #ifndef QIOSURFACEGRAPHICSBUFFER_H
+ #define QIOSURFACEGRAPHICSBUFFER_H
+ 
++#include <CoreGraphics/CGColorSpace.h>
+ #include <qpa/qplatformgraphicsbuffer.h>
+ #include <private/qcore_mac_p.h>
+