diff --git a/var/spack/repos/builtin/packages/mvapich/package.py b/var/spack/repos/builtin/packages/mvapich/package.py
index 37221fec277..de5d5e64942 100644
--- a/var/spack/repos/builtin/packages/mvapich/package.py
+++ b/var/spack/repos/builtin/packages/mvapich/package.py
@@ -69,7 +69,7 @@ class Mvapich(AutotoolsPackage):
         "pmi_version",
         description="Which pmi version to be used. If using pmi2 add it to your CFLAGS",
         default="simple",
-        values=("simple", "pmi2"),
+        values=("simple", "pmi2", "pmix"),
         multi=False,
     )
 
@@ -113,6 +113,7 @@ class Mvapich(AutotoolsPackage):
     depends_on("libfabric", when="netmod=ofi")
     depends_on("slurm", when="process_managers=slurm")
     depends_on("ucx", when="netmod=ucx")
+    depends_on("pmix", when="pmi_version=pmix")
 
     with when("process_managers=slurm"):
         conflicts("pmi_version=pmi2")
@@ -265,6 +266,8 @@ def configure_args(self):
 
         args.extend(self.enable_or_disable("alloca"))
         args.append("--with-pmi=" + spec.variants["pmi_version"].value)
+        if "pmi_version=pmix" in spec:
+            args.append("--with-pmix={0}".format(spec["pmix"].prefix))
 
         if "+debug" in self.spec:
             args.extend(