diff --git a/var/spack/repos/builtin/packages/pixman/package.py b/var/spack/repos/builtin/packages/pixman/package.py
index 422996cb017..e64568f595d 100644
--- a/var/spack/repos/builtin/packages/pixman/package.py
+++ b/var/spack/repos/builtin/packages/pixman/package.py
@@ -74,4 +74,8 @@ def configure_args(self):
             if self.spec.target.family == "aarch64":
                 args.append("--disable-arm-a64-neon")
 
+        # The Fujitsu compiler does not support assembler macros.
+        if self.spec.satisfies("%fj"):
+            args.append("--disable-arm-a64-neon")
+
         return args